Heart & Vascular

Advanced Heart Failure Comprehensive Care Center

(415) 502-4243

Each year, UCSF's Advanced Heart Failure Comprehensive Care Center (AHF CCC) treats and evaluates between 250 and 300 patients for heart failure. We are recognized internationally for our expertise in diagnosing and treating advanced heart failure.

We use remote monitoring to closely track our patients' status and provide state-of-the-art conventional and experimental drug and device therapies. Working with a broad team of heart specialists, we provide seamless coordinated care for our heart failure patients. Depending on the cause of the heart failure, treatment may include:

If those therapies aren't successful, a heart transplant may be an option. Since 1989, the AHF CCC has performed nearly 600 heart transplants. We are the sixth largest heart transplant program in the nation and continue to grow rapidly.

We are constantly exploring new technologies that allow us to accept donor hearts that could not have been accepted in the past. This innovative approach means that we have access to more donor hearts and are able to reduce waitlist times for patients requiring a heart transplant.

As a national leader in advanced heart failure care we are dedicated to finding new effective therapies. Eligible patients may be able to take part in clinical trials for heart failure treatment. Learn more about the process and benefits of participating in a clinical trial.

Doctor referral required

Our locations (3)

    Conditions we treat

    Treatments we specialize in

    Our team

    Awards & recognition

    • U S News and World Report badge recognizing UCSF as part of its 2024-2025 Honor Roll

      Among the top hospitals in the nation

    • One of the nation's best for heart & vascular surgery

    • Rated high-performing hospital for heart bypass surgery

    • Rated high-performing hospital for heart failure

    Decorative Caduceus

    The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least...

    Freedom from a composite of major adverse events (defined as Device Embolization, Vessel Erosion, Cardiac Perforation, and occurrence of cardiac surgery or percutaneous coronary intervention) in the Intervention group is greater t...

    Recruiting

    Decorative Caduceus

    ALT-FLOW II Trial of the Edwards APTURE Transcatheter Shunt System

    Shunt implant safety: proportion of patients in the APTURE shunt group without any serious device or procedure-related (CEC adjudicated) complications (i.e., Major Adverse Cardiovascular, Cerebrovascular, and Renal Events [MACCRE]...

    Recruiting

    Decorative Caduceus

    Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Eject...

    New York Heart Association classification (I, II, III or IV)

    Recruiting

    Decorative Caduceus

    A Study of a Mean Pulmonary Artery Pressure-Targeted Approach With Early and Rapid Treprostinil...

    Recruiting

    Decorative Caduceus

    Levothyroxine Supplementation for Heart Transplant Recipients

    Measured using the vasoactive-inotropic score (VIS) scale. VIS calculation: dopamine dose (μg/kg/min) + dobutamine dose (μg/kg/min) + 100 × epinephrine dose (μg/kg/min) + 10 × milrinone dose (μg/kg/min) + 10 000 × vasopressin dos...

    Recruiting

    Decorative Caduceus

    Reducing Right Ventricular Failure in Pulmonary Arterial Hypertension (RELIEVE-PAH)

    Percentage of Treatment group patients experiencing any device-related Major Adverse Cardiovascular or Neurological Events (MACNE) during the first 90-days after implantation

    Recruiting

    Decorative Caduceus

    Remote Dielectric Sensing (ReDS) Assisted Diuresis in Acute Decompensated Heart Failure

    Cumulative net fluid balance assessed by In's and Out's recorded in the Electronic Medical Record (EMR) during hospitalization

    Recruiting

    Decorative Caduceus

    Pulmonary Hypertension Association Registry

    PAH guideline-recommended diagnostics assessed include chest radiography, echocardiogram, ventilation-perfusion (V/Q) scan, pulmonary function tests, overnight oximetry, and right heart catheterization and identified as either "co...

    Recruiting

    Decorative Caduceus

    DORAYA-HF Early Feasibility Study

    Device or procedure related SAEs rate (including MACE) based on CEC adjudication.

    Recruiting

    Decorative Caduceus

    AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SY...

    Until the end of the study, each participant will be assigned to one of the following event outcomes: 1. Having at least one protocol-defined Heart Failure Event (HFE) in the CORE period 2. Having no Heart Failure Event (HFE...

    Recruiting

    Support services

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    Patient Resource

    Case Management & Social Work

    Connect with a team that can help you find resources, solve problems and advocate for you during treatment at UCSF.

    Class

    Mindfulness-Based Stress Reduction Class

    This eight-week class teaches mindfulness practices that can reduce stress and improve your overall health, such as meditation and body awareness.

    Patient Resource

    Patient Relations

    We welcome feedback about your experience at UCSF Health. Find out how to contact us with comments, questions or concerns.

    Patient Resource

    Spiritual Care Services

    Chaplains representing many faiths are available around the clock to provide support, comfort and counsel to patients, families and caregivers.

    Preparing for your appointment

    What to Bring

    • Echocardiogram results from within last 6 months on CD, if available
    • Photo I.D.
    • Health insurance card
    • Insurance authorization, if required
    • Doctor's referral, if required
    • List of your medications, including dosages, plus any you're allergic to
    • List of questions you may have
    • Device or paper for taking notes

    International Services

    If you live outside the United States and are coming to UCSF for medical treatment, our patient liaisons can help coordinate all aspects of your visit.

    Learn more

    Interpreting Services

    UCSF offers interpreters in various languages, including American Sign Language (ASL), as well as services for deaf, hard-of-hearing and visually impaired patients.

    Learn more

    Hospital Stays

    Make your hospital stay as smooth and comfortable as possible by finding out how to prepare and what to expect.

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    Your Doctor Visit

    See our top 10 tips for making your UCSF doctor’s appointment as stress-free and productive as possible.

    Learn more

    Related clinics

    Cardiac Electrophysiology and Arrhythmia Service

    400 Parnassus Ave., Fifth Floor
    San Francisco, CA 94143

    (415) 353-2554
    M-F, 8 a.m. - 5 p.m.

    Cardiac Surgery Program

    See our two Bay Area locations and learn more about the program.

    M-F, 8 a.m. - 5 p.m.

    Heart Transplant Program

    400 Parnassus Ave., Fifth Floor
    San Francisco, CA 94143

    (415) 502-4243
    Thursdays, 8 a.m. - 5 p.m.

    Mechanical Circulatory Support

    400 Parnassus Ave., Fifth Floor
    San Francisco, CA 94143

    (415) 502-4243
    M-F, 8 a.m. - 5 p.m.

    San Mateo Primary and Specialty Care

    1100 Park Place, Suite 100
    San Mateo, CA 94403

    (415) 502-8950
    M-F, 8 a.m. - 5 p.m.

    Our research initiatives

    • UCSF-Division-of-Cardiology-Research-2x

      UCSF Division of Cardiology Research

      Researchers at the UCSF Division of Cardiology investigate all aspects of heart disorders, from how disease develops to who is most at risk, with an emphasis on translating key findings into more effective care.

      Learn more

    Do you need pediatric care?

    UCSF Benioff Children's Hospitals
    UCSF Benioff Children's Hospitals

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