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Interventional Cardiology Program

The UCSF Interventional Cardiology Program brings highly specialized providers together to care for patients with heart conditions. Working as a team, we tailor treatments to specific needs and create individualized plans. As our patient, you are part of the care team, and we work with you to identify the most effective and safest treatment for your heart condition.

Collaboration is essential to our mission. On your behalf, we first consult with our colleagues who specialize in cardiac surgery, vascular (blood vessel) surgery and electrophysiology (testing to assess the heart's electrical system), as well as those who specialize in specific conditions, such as advanced heart failure and adult congenital heart disease (heart defects present at birth). We then share these experts’ guidance to help you and your referring provider make informed decisions on your care.

Our program offers advanced therapies that aren’t commonly available at other hospitals. And our specialists take pride in finding ways to treat patients previously told they had no options.

The program focuses on the following services:

Complex diagnostics and treatments for problems with coronary arteries. The coronary arteries supply the heart with oxygenated blood. When they become narrowed or blocked, such as in chronic total occlusion, we can perform advanced techniques, such as antegrade and retrograde treatment approaches and left main stenting (placing a mesh tube to keep the vessel open). We also provide comprehensive physical assessments to diagnose other cardiovascular conditions, such as microvascular disease (when small blood vessels aren’t working correctly) and coronary vasospasm (when muscle tissues in the heart’s arteries temporarily contract).

Structural and valve treatments. We have expertise in advanced techniques to address problems with the heart's valves. These include transcatheter aortic valve replacement (TAVR), mitral and tricuspid transcatheter edge-to-edge repair (TEER), and transcatheter mitral and tricuspid valve replacement (TMVR and TTVR). (Transcatheter interventions are less invasive methods that use a thin, flexible tube called a catheter, which cardiologists thread through blood vessels to reach the heart.)

Transcatheter treatments for heart failure and pulmonary hypertension. This includes using mechanical support devices, creating transcatheter shunts (passageways for fluid) and performing balloon pulmonary angioplasty (opening up blood vessels to address high blood pressure in the lungs caused by chronic blood clots).

Adult congenital heart disease treatments. We perform procedures to close a hole in the heart, such as patent foramen ovale (PFO) or atrial septal defect (ASD), as well as interventions for pulmonary valve conditions.

The fellowship-trained, board-certified interventional cardiologists on our team are recognized leaders in the field. In addition to patients who live in the San Francisco Bay Area, we welcome many who travel thousands of miles to receive our care.

Requests for second opinions are welcome, and we’re happy to discuss treatments that can meet individual goals for improved heart health.

Because our program is active in numerous clinical trials (studies to evaluate promising treatments), our patients have easy access to therapies that few other medical centers can provide.

"What I am going through is a scary thing. Having the team of people working at UCSF has made me feel I am not going through this alone." – Interventional Cardiology Program patient

Our locations (2)

    Decorative Caduceus

    MitraClip REPAIR MR Study

    The proportion of subjects who are alive, without stroke, CV hospitalization or acute kidney injury requiring renal replacement therapy at 2 years in the Device and Control groups, respectively

    Recruiting

    Decorative Caduceus

    Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial

    Comparison of number of participants with composite endpoint events between experimental and active comparator arms

    Recruiting

    Decorative Caduceus

    Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial

    Recruiting

    Decorative Caduceus

    Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY...

    Composite score of all-cause mortality, valve re-intervention, hospitalizations and urgent visits for heart failure, or onset of ≥ 3+ MR (by transthoracic echocardiogram (TTE)) from randomization to a minimum follow-up of 3 years ...

    Recruiting

    Decorative Caduceus

    ALT-FLOW II Trial of the Edwards APTURE Transcatheter Shunt System

    Shunt implant safety: proportion of patients in the APTURE shunt group without any serious device or procedure-related (CEC adjudicated) complications (i.e., Major Adverse Cardiovascular, Cerebrovascular, and Renal Events [MACCRE]...

    Recruiting

    Decorative Caduceus

    SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncont...

    The Primary endpoint of office Systolic Blood Pressure (SBP) change at 6 months will be assessed for all patients in the Main Study Cohort

    Recruiting

    Decorative Caduceus

    A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on...

    To demonstrate the superiority of pelacarsen (TQJ230) vs. placebo in slowing the progression of calcific aortic valve stenosis by evaluating the change from baseline to month 36 in peak aortic jet velocity by echocardiography

    Recruiting

    Decorative Caduceus

    Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Eject...

    New York Heart Association classification (I, II, III or IV)

    Recruiting

    Decorative Caduceus

    Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

    Incidence of Major Adverse Events

    Recruiting

    Awards & recognition

    • U S  News and World Report badge recognizing UCSF as part of its 2024-2025 Honor Roll

      Among the top hospitals in the nation

    • U S News and World Report badge recognizing UCSF among the Best Hospitals for Heart and Vascular, 2024-2025

      One of the nation's best for heart & vascular surgery

    • U S News and World Report badge recognizing UCSF among the High Performing Hospitals for Heart Failure, 2024-2025

      Rated high-performing hospital for heart failure

    • Recognized for providing optimal care for heart attack patients

    Support services

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    Patient Resource

    Case Management & Social Work

    Connect with a team that can help you find resources, solve problems and advocate for you during treatment at UCSF.

    Class

    Mindfulness-Based Stress Reduction Class

    This eight-week class teaches mindfulness practices that can reduce stress and improve your overall health, such as meditation and body awareness.

    Patient Resource

    Patient Relations

    We welcome feedback about your experience at UCSF Health. Find out how to contact us with comments, questions or concerns.

    Patient Resource

    Spiritual Care Services

    Chaplains representing many faiths are available around the clock to provide support, comfort and counsel to patients, families and caregivers.

    Preparing for your appointment

    What to Bring

    • Photo I.D.
    • Health insurance card
    • Insurance authorization, if required
    • Doctor's referral, if required
    • Recent test results related to your condition
    • List of your medications, including dosages, plus any you're allergic to
    • List of questions you may have
    • Device or paper for taking notes

    International Services

    If you live outside the United States and are coming to UCSF for medical treatment, our patient liaisons can help coordinate all aspects of your visit.

    Learn more

    Interpreting Services

    UCSF offers interpreters in various languages, including American Sign Language (ASL), as well as services for deaf, hard-of-hearing and visually impaired patients.

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    Hospital Stays

    Make your hospital stay as smooth and comfortable as possible by finding out how to prepare and what to expect.

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    Your Doctor Visit

    See our top 10 tips for making your UCSF doctor’s appointment as stress-free and productive as possible.

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    Related clinics

    Heart Valve Disease Clinic

    535 Mission Bay Blvd. South
    San Francisco, CA 94158

    Cardiovascular Care and Prevention Center at Mission Bay

    535 Mission Bay Blvd. South
    San Francisco, CA 94158

    Cardiovascular Care and Prevention Center at Parnassus

    400 Parnassus Ave., Suite 501
    San Francisco, CA 94143

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